Product Name: Bitter Sophora Root Extract
Botanical Name: Sophora flavescens
Part Used: Root
Specification: 4:1 5:1 8:1
Molecular Formula: C15H24N2O
Molecular Weight: 248.3639
Appearance: White needle crystal
Brand Name: Changsha Nutramax Inc.
Model Number: Nutramax-BARE
What is Bitter Sophora Root Extract produced in Changsha NutraMax Inc.?
Matrine and oxymatrine are the two major alkaloid components found in sophora roots. They are obtained primarily from Sophora japonica (kushen), but also from Sophora subprostrata (shandougen), and from the above ground portion of Sophora alopecuroides. The matrines were first isolated and identified in 1958;they are unique tetracyclo-quinolizindine alkaloids found only in Sophora species thus far. An intensive investigation into the pharmacology and clinical applications of these alkaloids has gone on for the past decade and remains one of the focal points of Chinese medical research. The main clinical applications are treatment of people with cancer, viral hepatitis, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema).
Where will NutraMax’s Bitter Sophora Root Extract be used to?
In recent years, oxymatrine has been recommended for treating chronic hepatitis B and chronic hepatitis C and has been shown effective in clinical practice. It has been utilized for these applications broadly, but the factors affecting its efficacy have not yet been determined.
Sophora and its alkaloids are commonly used in China for treatment of heart arrhythmias. A possible mechanism of action is to help block sodium and calcium channels, a mechanism relied on by several antiarrhythmic pharmaceuticals.
Sophora is frequently used in treatment of skin diseases, applied topically and consumed orally. One of the primary uses for topical therapy is treatment of vaginitis, particularly that due to candida infection.
Application of NutraMax’s Bitter Sophora Root Extract
Treat chronic hepatitis B and chronic hepatitis C,
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